Epiphen vs Phenoleptil - same drug?

Yes, identical molecule. Use whichever your prescription specifies and whichever pharmacy stocks the right strength.

Can I switch brands mid-course?

On veterinary advice yes - bioequivalent, but switching should be done with serum level monitoring.

Epiphen price comparison UK

Alternative phenobarbital brand to Phenoleptil. Same molecule, different presentation. Controlled drug (Schedule 3). Active ingredient: phenobarbital. Below: compare UK vet prices with VMD-approved online pharmacies for your dog's weight.

Dog weight (kg)Your vet's price per month (optional, £)

Typical vet price

£41.00–£59.00/mo

indicative UK range

Cheapest online

£11.97/mo

Pet Drugs Online

Annual saving

£348.36–£564.36

after £21 prescription fee: £327.36–£543.36

Based on a 15 kg dog, recommended strength: 30 mg. Assumes 12 months of continuous use (chronic dosing) and one written prescription per year. CMA Order caps the prescription fee at £21 for the first medicine, plus £12.50 per additional medicine on the same prescription. Prices are indicative and last verified 2026-05-15. Always confirm the current price on the pharmacy site before purchase.

Pharmacy	Pack	Pack price	Monthly cost	Buy
Pet Drugs Online VMD approved · Free over £39	100 tablets	£19.95	£11.97 Best value	Buy from Pet Drugs Online
Animed Direct VMD approved · Free over £29, next-day available	100 tablets	£21.15	£12.69	Buy from Animed Direct
VetUK VMD approved · Free over £29	100 tablets	£22.54	£13.52	Buy from VetUK

What Epiphen treats

Alternative phenobarbital brand to Phenoleptil. Same molecule, different presentation. Controlled drug (Schedule 3).

Why it costs more at the vet

Dechra-branded phenobarbital; pricing structurally similar to Phenoleptil.

Ready to switch? It takes 5 minutes.

Email template, prescription steps and refill setup — the full path from "I just paid too much at the vet" to "I'm saving £X every month".

Open the 5-minute switch guide →

How to get a written prescription

The CMA Order is legally binding by 23 September 2026. Every UK vet must offer a written prescription on request, with the fee capped at £21 for the first medicine plus £12.5 per additional medicine on the same prescription. Take the prescription to any VMD-approved online pharmacy listed above. We have a short guide with a template email you can send to your practice.

Read the full prescription guide →

Common side effects

Sedation (early)
Polyphagia
Hepatic enzyme elevation

This is not a complete list. Always read the patient information leaflet and speak to your vet about side effects.

FAQ

Epiphen vs Phenoleptil - same drug?: Yes, identical molecule. Use whichever your prescription specifies and whichever pharmacy stocks the right strength.
Can I switch brands mid-course?: On veterinary advice yes - bioequivalent, but switching should be done with serum level monitoring.

Related medications

Anti-epileptic

Phenoleptil

First- or second-line antiepileptic for idiopathic epilepsy. Phenobarbital is a controlled drug (Schedule 3) - written prescription mandatory.

First-line antiepileptic for idiopathic epilepsy in dogs. Twice-daily dosing. Lifelong therapy with substantial cumulative savings online.

Adjunctive antiepileptic added to phenobarbital or imepitoin when seizure control is incomplete on monotherapy.

Track Epiphen price drops

We'll email when Epiphen drops in price at any of the pharmacies above.

Pricing data status: indicative. Last verified 2026-05-15. Pharmacies change prices regularly - always confirm before purchase. Not medical advice.